Browse the latest forensic toxicology articles or search the collection.
-
What Did Two Million Clinical Urine Tests Show About Methamphetamine Trends?
A large clinical testing dataset showed rising adjusted methamphetamine positivity. Its selected population, changing test menus and copositivity measures do not establish national prevalence or simultaneous use.
-
How Representative Is the Evidence for Digital Methamphetamine Interventions?
A 2026 scoping review mapped 15 studies and 13 digital interventions. Gender imbalance, attrition and mixed definitions of success limit general claims about effectiveness.
-
Can Childhood DNA Methylation Prove Lasting Injury From Prenatal Methamphetamine Exposure?
A 100-child study linked prenatal exposure and early adversity to one saliva-DNA methylation site. The finding did not establish brain injury, gene activity or an individual diagnostic test.
-
Does Methamphetamine Use Explain Why People Leave Opioid Medication Treatment?
Eight observational studies associated methamphetamine use with lower opioid-treatment retention. Different discharge definitions and service contexts prevent a single causal interpretation.
-
Does a Sex Difference in Methamphetamine-Treated Mice Predict Human Cardiac Susceptibility?
A five-month mouse experiment found greater male cardiac effects and mortality. Dose schedule, survivor selection and untested hormone explanations limit translation to individual people.
-
Methamphetamine and Cardiomyopathy in Taiwan: Why Rates, Hazards and Diagnostic Codes Need Separate Reading
A 2025 claims study reported an association with later cardiomyopathy. Its person-time rates, diagnostic exposure definition and internal inconsistencies limit how that finding can be used.
-
Did Modafinil Improve Methamphetamine Treatment Outcomes in a 71-Person Randomized Trial?
A historical placebo-controlled trial found no overall urine-test or retention advantage from modafinil. Post hoc attendance subgroups did not establish a responsive population.
-
Why Authentic Specimens Matter in Cannabinoid Assay Validation
A serum study found an interfering cannabinoid-related compound that blank and fortified samples missed. Its lesson concerns selectivity, not proof of error in every postmortem test.
-
Vitreous Ethanol Prediction: Why a Narrow Slope Interval Can Hide Wide Individual Uncertainty
In 345 autopsies, a precise regression slope did not yield a precise blood ethanol estimate for an individual. Published prediction intervals show the difference numerically.
-
Does a Warm-Climate Ethanol Study Validate Testing in Advanced Decomposition?
A Brazilian study examined 21 ethanol-positive cases only 3–8 hours after death, with minimal decomposition and refrigerated specimens. Geography did not make it a warm-storage experiment.
-
Does Measuring THC in Brain Tissue Establish Impairment Before Death?
A 43-case cannabinoid study found variable blood–brain distributions. Brain detection added specimen information but did not establish driving impairment or crash causation.
-
Mirtazapine Detected After Death: What a 13-Case Series Says About Causation
Mirtazapine appeared across several autopsy specimens without being assigned a causal role in any of 13 deaths. The series provides context, not a universal safe or fatal concentration.
-
Does 91% Expert Agreement Mean 91% Accuracy in Diagnosing Methamphetamine Psychosis?
A 2024 panel endorsed proposed diagnostic criteria. Agreement among 22 physicians is different from accuracy measured against patient outcomes or an independent reference standard.
-
Is the DBH Paranoia Association a Validated Methamphetamine Genetic Test?
A Thai candidate-gene study reported a nominal association that did not survive multiple-testing correction. Its clinical and genetic samples had different denominators.
-
Does Reporting Heroin and Methamphetamine Injection Mean They Were Mixed Together?
A Denver survey separated same-year use from usual simultaneous injection. Its overdose association was a prevalence comparison, not proof of the drugs present during an event.
-
Can N,N-Dimethylamphetamine in Wastewater Identify Methamphetamine Smoking?
A proposed smoking marker also occurs as a synthesis impurity. A 2018 study shows why contemporary seizure data and excretion assumptions matter.
-
Can a Graphene Methamphetamine Sensor Miss a High-Purity Seized Sample?
A 2023 sensor study detected eight of nine methamphetamine-containing powders. Its missed sample and interference findings limit broad claims of screening reliability.
-
What Does One “Methamphetamine Alone” Death Among 506 Selected Cases Mean?
A Victorian coroner study’s rare strictly classified mono-toxicity finding describes selected deaths, not the fatality risk of methamphetamine use.
-
Do Human PET Studies Consistently Show Brain Inflammation After Methamphetamine Use?
Three human PET studies produced different TSPO findings. Tracer choice, modeling, abstinence duration and selected populations limit simple conclusions about microglial activation.
-
Does Baboon PET Validation Establish a Human Methamphetamine Injury Threshold?
A 1998 animal experiment linked PET transporter changes with postmortem markers. Its repeated intramuscular regimen does not supply a human dose or blood threshold.